By Johannes Ring
This publication provides the cutting-edge in examine into atopic dermatitis, or atopic eczema, and offers quite a few powerful useful administration thoughts which are grounded within the enormous medical adventure of the writer. a systematic evidence-based method of the topic is followed, progressing from medical indicators in numerous ailment levels, molecular genetics, and pathophysiology via to therapy and prevention. All elements of sufferer administration are lined, together with diagnostics, avoidance thoughts, emollient treatment, and acute remedy of eczema and itch. assorted distinctive healing techniques are mentioned, starting from glucocorticoids, topical calcineurin inhibitors, and antimicrobial remedy via to UV remedy, allergen-specific immunotherapy, systemic immunosuppressive treatment, and rising strategies. Environmental affects are thought of, and there's a concentrate on the complete man or woman, with cognizance to psychosocial facets of the sickness and the advantage of academic courses similar to “eczema schools”. Atopic Dermatitis should be useful for dermatologists, allergists, pediatricians, and common practitioners and informative for different people and sufferers.
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Additional resources for Atopic Dermatitis: Eczema
229 six-year-old children in Germany 1991–2000 (According to Möhrenschlager et al. (2006b)) Atopic Eczema (%) 8 Total IgE (< 180 kU/l) 5,9 3,2 6 4 2 0,7 0,8 0,7 Only allergic against house dust mite Allergic against house dust mite plus grass pollen 0,7 0,7 3,9 1,1 1,7 1,6 Girls (n = 2418) Boys (n = 2333) 0 4,1 Only allergic against pollen 1 18 General Introduction and Epidemiology Thomas Bieber therefore postulated that atopic eczema always starts as an “intrinsic” condition, possibly on the basis of a disturbed skin barrier function (see Sect.
In 80 %, atopic eczema starts in early childhood (under 2 years), and in recent years an increase of prevalence in adults can be observed. Only one third of the children with atopic eczema are losing the disease before puberty; in two thirds of the children affected, it can be estimated that eczema stays or reoccurs in adulthood. Risk factors from epidemiologic studies are higher socioeconomic status (as measured as educational level of parents), psychosomatic influences, alterations in the course of pregnancy, allergen exposure (especially pet keeping), and pollutant exposure (especially tobacco smoke in indoor and traffic exposure in outdoor air).
2010). Psychosomatic factors do not only influence the course of an existing eczema, but might also be of relevance in the early initiation and triggering of first symptoms. 63) (Olesen et al. 1997). 4 Hygiene, Infectious Disease and Vaccinations The general aspects of the so-called hygiene or jungle hypothesis (see above) are discussed elsewhere. The question as to a possible benefit or risk of vaccination is controversially discussed. Measles In a large study from Denmark, 9744 children at the age of 3–15 years were investigated for the influence of measles.
Atopic Dermatitis: Eczema by Johannes Ring